Wednesday, November 19, 2025

DNA-Based Nanodevice Breakthrough Enables Near-Infrared Light-Controlled Drug Release & Bioimaging


A team of nanotechnology researchers has unveiled a revolutionary DNA-based nanodevice that uses near-infrared (NIR) light to deliver precision-controlled drug release while simultaneously enabling high-resolution bioimaging. This next-generation platform brings scientists one step closer to safer, smarter, and more targeted therapies for complex diseases such as cancer.

Built from carefully engineered DNA structures, the nanodevice functions like a programmable molecular capsule. When exposed to NIR light, the capsule undergoes a structural change, triggering the on-demand release of therapeutic molecules. Because NIR light can penetrate deep into tissues without causing damage, this method offers exceptional control and minimal invasiveness.

What makes this innovation particularly exciting is its dual functionality. Along with drug delivery, the DNA construct is integrated with imaging agents that allow real-time visualization inside the body. This means clinicians could track where the drug is going and how it is being released all with a single multifunctional nanoplatform.

Researchers believe this technology could pave the way for precision medicine, enabling patient-specific treatments with fewer side effects. As the field of DNA nanotechnology continues to grow, such light-responsive systems are expected to transform targeted therapies, diagnostics, and future biomedical devices.

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Theme: Popular Engineer Awards for a Connected Future

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